Çocuk Sağlığı ve Hastalıkları Dergisi 2020 , Vol 63 , Num 1-4
The clinic and biochemical features of polycystic ovary syndrome in adolescents
Damla Kazar Ağaçkıran *1 ,Melis Pehlivantürk Kızılkan *2 ,Sinem Akgül *3 ,Nuray Kanbur *4 ,Orhan Derman *4
1 Hacettepe Üniversitesi Tıp Fakültesi, Pediatri Uzmanı, Ankara
2 Hacettepe Üniversitesi Tıp Fakültesi, Pediatri Doktora Öğretim Üyesi, Ankara
3 Hacettepe Üniversitesi Tıp Fakültesi, Pediatri Doçenti, Ankara
4 Hacettepe Üniversitesi Tıp Fakültesi,Pediatri Profesörü, Ankara
Kazar Ağaçkıran D, Pehlivantürk Kızılkan M, Akgül S, Kanbur N, Derman O. (Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey). The clinic and biochemical features of polycystic ovary syndrome in adolescents. Çocuk Sağlığı ve Hastalıkları Dergisi 2020; 63: 9-13.

Signs and symptoms of polycystic ovary syndrome (PCOS) begin during adolescence. According to the the Pediatric Endocrine Society the diagnostic criteria for PCOS for adolescents include chronic anovulation with biochemical and/or clinical hyperandrogenism. The aim of this study was to evaluate the biochemical and clinical findings of PCOS in adolescents between 13-18 years of age diagnosed and followed at Hacettepe University İhsan Doğramacı Children`s Hospital Division of Adolescent Medicine. Patients were divided into 4 groups according to the phenotypic application model. The patients` mean age was 15.6 ± 1.3 years and the mean menarche age was 12.2 ± 1.3 years (10.0 - 15.4 years). Acne was detected in 32 (61.5%) patients, acantosis nigricans in 6 (11.5%), dyslipidemia in 20 (37%) and HOMA-IR >2.5 in 19 (35.2%) patients. Forty (76.9%) patients had biochemical and 44 (84.6%) patients had clinical hyperandrogenism. According to PCOS phenotypic application model, 37 (71.2%) group 1, seven (13.5%) group 2, four (7.7%) group 3 and four (7%) group 4. The debate concerning the diagnostic criteria for PCOS for adolescents continues. Hyperandrogenism and chronic anovulation differ for adolescents. It is important to continue to follow patients who do not meet the full diagnostic criteria to enable early diagnosis. Anahtar Kelimeler : polycystic ovary syndrome, chronic anovulation, hyperandrogenism, adolescence

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