Çocuk Sağlığı ve Hastalıkları Dergisi 2007 , Vol 50 , Num 3
New strategies in inotropic treatment
Benan Bayrakçı1, Tevfik Karagöz2
1Hacettepe Üniversitesi Tıp Fakültesi, Pediatri Yardımcı Doçenti
2Hacettepe Üniversitesi Tıp Fakültesi, Pediatri Doçenti
Bayrakçı B, Karagöz T. (Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey). New strategies in inotropic treatment. Çocuk Sağlığı ve Hastalıkları Dergisi 2007; 50: 201-209.

Though human curiosity of heart is rooted in prehistoric ages, the complexity of its function, ion channels, molecular aspects and protein conformations have barely been discovered even in the present century. Circulatory failure in children is a heterogeneous group of disorders, which may be caused by congenital defects or myocardial dysfunction based on metabolic, toxic or inflammatory pathologies, which occasionally require multi-drug treatments. As our knowledge and understanding of the myocardial functions and exitationcontraction coupling increase, further strategies target interventions to highly specific perturbations of cellular function, neurohormonal pathways and genetic solutions. In this paper, our goal is to review the newest strategies and novel treatment alternatives of the inotropic era. Anahtar Kelimeler : inotrop, vazopressör, çocuk, kalp yetmezliği, katekolamin, dolaşım, inotrope, vasopressor, pediatric, heart failure, catecholamine, circulation

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