Çocuk Sağlığı ve Hastalıkları Dergisi 2007 , Vol 50 , Num 4
Serum hyaluronic acid level in preterms: can it predict bronchopulmonary dysplasia?
Tuğba Gürsoy1, Gülsevin Tekinalp2, Ayşe Lale Doğan3, Mutlu Hayran4, Şule Yiğit2, Murat Yurdakök2
1Hacettepe Üniversitesi Tıp Fakültesi Neonatoloji Uzmanı
2Hacettepe Üniversitesi Tıp Fakültesi Pediatri Profesörü
3Hacettepe Üniversitesi Tıp Fakültesi Biyokimya Doçenti
4Hacettepe Üniversitesi Tıp Fakültesi Halk Sağlığı Yardımcı Doçenti
Gürsoy T, Tekinalp G, Doğan AL, Hayran M, Yiğit Ş, Yurdakök M. (Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey). Serum hyaluronic acid level in preterms: can it predict bronchopulmonary dysplasia? Çocuk Sağlığı ve Hastalıkları Dergisi 2007; 50: 227-230.

Fetal tissues contain high concentrations of hyaluronic acid (HA) concentrations of which were shown to increase in lung diseases. Here, we aimed to evaluate whether serum HA levels in preterm babies can predict bronchopulmonary dysplasia. The study group consisted of 12 neonates who developed respiratory distress syndrome upon admission and bronchopulmonary dysplasia later. The control group consisted of 13 neonates who developed neither of these pathologies. There was no significant difference in HA levels of the groups; therefore, serum HA levels are unlikely to be used as a predictor of bronchopulmonary dysplasia. Anahtar Kelimeler : Bronkopulmoner displazi, hyaluronik asit, prematüre, Bronchopulmonary dysplasia, hyaluronic acid, premature

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