Çocuk Sağlığı ve Hastalıkları Dergisi 2010 , Vol 53 , Num 2
Intrauterine heavy metal exposure
Arzu Sonçağ1, Kadriye Yurdakök2
Hacettepe Üniversitesi Tıp Fakültesi 1Pediatri Uzmanı, 2Pediatri Profesörü Toxic heavy metals are the majör source of environmental pollution in this new millennium. The most common toxic heavy metals are lead, mercury and cadmium. There is no known function of these toxic heavy metals in the human body in females, toxic heavy metals can accumulate in the body, have deleterious health effects and may affect the pregnancy metabolism and the fetus. Toxic heavy metals accumulated in the body before the pregnancy can be transferred to the fetus via the umbilical cord. Lead can be mobilized together with calcium during bone metabolism and may be transferred to the fetus by the transplacental route or by lactation during breastfeeding. Intrauterine lead exposure can cause growth retardation, cognitive dysfunction, low IQ, low scores on ability tests, and low performance in school. Signs and symptoms of prenatal mercury exposure can start in parallel to the developmental status. Intrauterine mercury exposure may cause mental retardation, cerebral palsy, movement disorders, and visual, speech and hearing disorders. Although it has been shown that the transmission of cadmium to the fetus is very limited by the transplacental route or by breastfeeding, cadmium can be teratogenic in animals and may affect the developmental stages of the fetus. Animal studies have demonstrated that intrauterine cadmium exposure may cause low birth weight, amelia, late ossification of the sternum and costae, and behavioral changes. Anahtar Kelimeler : yenidoğan, çevre kirliliği, ağır toksik metaller.
Copyright © 2016 cshd.org.tr