Çocuk Sağlığı ve Hastalıkları Dergisi 2014 , Vol 57 , Num 1
Iatrogenic Cushing syndrome due to topical corticosteroid in an infant with ichthyosis: a case report
*Aysel Vehapoğlu Türkmen1 Mustafa Atilla Nursoy2, Serdar Türkmen3, Mehmet Yazıcı4
Bezmiâlem Vakıf Üniversitesi 1Pediatri Uzmanı, 2Pediatri Yardımcı Doçenti, Bakırköy Sadi Konuk Eğitim ve Araştırma Hastanesi 3Klinik Biyokimya Uzmanı, İstanbul Eğitim ve Araştırma Hastanesi 4Çocuk Cerrahisi Uzmanı *İletişim: ayvahap@hotmail.com Topical corticosteroids are one of the oldest and most frequently used treatments for dermatologic conditions. Corticosteroids are absorbed easily through the skin, and this may lead to a varying degree of suppression of the hypothalamic-pituitary-adrenal axis. Herein, we report a seven-month-old female infant with ichthyosis who developed iatrogenic Cushing's syndrome after diaper dermatitis treatment involving the extensive misuse of topical diflucortolone valerate prescribed by the physician. We also discuss the effects of topical steroids on the adrenal axis. The body surface area in children is so large in comparison to the body mass, and their skin is thin; hence, they may readily suffer the systemic side effects of the percutaneous absorption of corticosteroids. Awareness of the side effects is important when prescribing steroid-containing medication, especially during childhood. Anahtar Kelimeler : kortikosteroidler, iatrojenik Cushing sendromu, iktiyozis, süt çocukluğu.
Copyright © 2016 cshd.org.tr