Çocuk Sağlığı ve Hastalıkları Dergisi 2015 , Vol 58 , Num 4
Demographic and clinical characteristics and bone-mineral metabolism of pediatric cerebral palsy patients
*Mehmet Can Yeşilmen1, Mihriban Özlem Hergüner2, Bilgin Yüksel2, Şakir Altunbaşak2, Faruk İncecik3, Gülen Gül Mert1, Eser Aynacı1, Şeyda Besen1, Zeliha Haytoğlu1
Çukurova Üniversitesi Tıp Fakültesi 1Pediatri Uzmanı, 2Pediatri Profesörü, 3Pediatri Doçenti
*İletişim: m.can62@hotmail.com
Yeşilmen MC, Hergüner MÖ, Yüksel B, Altunbaşak Ş, İncecik F, Mert GG, Aynacı E, Besen Ş, Haytoğlu Z. (Çukurova University Faculty of Medicine, Department of Pediatrics, Adana, Turkey). Demographic and clinical characteristics and bone-mineral metabolism of pediatric cerebral palsy patients. Çocuk Sağlığı ve Hastalıkları Dergisi 2015; 58: 140-151.

The aim of the study is to evaluate clinic and demographic properties, detect bone mineral metabolism problems and raise awareness of these problems of cerebral palsy (CP) patients who are followed up in Çukurova University Pediatric Neurology Department. 102 patients aged 2-18 years who are regularly followed up in Çukurova University Pediatric Neurology Department, between January 2014-January 2015 are involved in this study. Demographic characteristics, etiologies, clinic and laboratory findings and associated problems of these patients are evaluated. Mean age of patients were 96.83 ± 53.54 months (24-207 months), male/female ratio was 1,2. 23.5% of the percents were born term and 50% patients’ birth weight was above 2500 gr. Spastic Quadriplegia was the most frequent type (38.2%). Most frequent etiologic factor was natal factors (56.9%). In detailed etiologic evaluation, asphyxia (49%) and low birth weight (28.4%) were most seen. Most frequent cerebral MRI abnormality was periventricular leukomalacia (25%). Other accompanying problems were mental retardation 88.2%, speech problems (72.5%), malnutrition (67.6%), epilepsy (46.4%), visual problems (28.4%). Levels of osteocalcin, IGF-1, IGFBP-3 and PTH were better in patients who were on regular physiotherapy (p<0.05). Serum 25(OH)D3 levels were correlated with sun exposure (p > 0.05). Enough and correct sun exposure and regular, dynamic physiotherapy may improve bone health. Regular follow-up of neuromotor development in patients with complicated birth and perinatal asphyxia may prevent delayed diagnosis and treatment. Anahtar Kelimeler : serebral palsi, asfiksi, kemik mineral bozukluğu.

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