Neonatal sepsis, characterized by systemic signs of infection in the first month of life, remains an important clinical syndrome. Despite advances in neonatology, it has high rates of mortality and morbidity, especially in developing countries. Early diagnosis and adequate antibiotic treatment are required. Several interleukins, tumor necrosis factor, procalcitonin, C-reactive protein, immunoglobulins, and other markers have been used in the diagnosis of sepsis. Culture is the gold standard laboratory technique for the diagnosis of neonatal sepsis. New diagnostic modalities have been developed in addition to traditional techniques. In this review, we sought to evaluate both the traditional and new modalities for the diagnosis of neonatal sepsis.

Keywords: neonatal sepsis, tanısal laboratuvar yöntemleri.