Guillain-Barré syndrome is an acute polyradiculoneuropathy with clinical features including progressive weakness of the limbs, decrease or absence of tendon reflexes, and sensory changes. Only a few patients have experienced recurrent Guillain-Barré syndrome, and the exact mechanism or risk factors are not yet known. In this report, we present an 11-year-old boy with a second attack of Guillain-Barré syndrome after total recovery from the first attack that occurred eight years before. In his second attack, he responded partially to the first intravenous immunoglobulin (IVIG) protocol, necessitating a second IVIG therapy. We emphasize that the families and patients should be informed about the risk of recurrence of Guillain-Barré syndrome and additionally that a second course of IVIG therapy could be an alternative to other treatment strategies in cases resistant to the first immunoglobulin course.

Keywords: Guillain-Barré sendromu, intravenöz immünoglobülin, tekrarlayan, Guillain-Barré syndrome, intravenous immunoglobulin, recurrent